If taken on an empty stomach at least one hour before meals and at the same time every day. Esomeprazole works best if taken on an empty stomach at least one hour before a meal. Nexium decreases the amount of acid backing up into the esophagus and causing reflux symptoms. Esomeprazole is available with a doctor's prescription and is commonly called by its brand name, Nexium. Use of Esomeprazole in pregnant women has not been appraised. What should my health care professional know before I take Esomeprazole? Esomeprazole capsules should be taken at least one hour before a meal. Nexium is used to treat and prevent stomach and intestinal ulcers, damage to the gastrointestinal tract caused by stomach acid or infection.
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