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Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. If you have any unusual stress such as a serious illness, fever or infection, or if you have any of these conditions, you may need a dose adjustment or special tests to safely take Prednisolone. Prednisone may interact with estrogens and phenytoin. You are allergic to Prednisolone, or if you have surgery or a medical emergency. Prednisone may interact with estrogens and phenytoin. Prednisone is used in so many conditions, only the most common or established uses are mentioned here. A day or a day and a half. Prednisone has very little mineral corticoid activity, so it is not used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly.
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