These changes might disturb the working of vital body systems. Unipolar depression due to death of their spouse, serious illnesses like diabetes, cancer, arthritis and heart ailments. Similarly, women facing harassment at work develop low self-confidence levels and a feeling of helplessness which may encourage the development of clinical depression. Such changes can trigger mental imbalances that translate into depression. If you have had an episode may not increase your chances of suffering from a major depression attack again.
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