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Individuals who have developed allergic reactions from aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib. This drug may rarely cause serious liver disease. Fluconazole increases the concentration of Celecoxib in the body by inhibiting the breakdown of Celecoxib in the liver. This drug may rarely cause serious liver disease. Celebrex is used to reduce pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
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