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Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. Flagyl possesses a wide spectrum of action in the attitude to anaerobic microorganisms. Metronidazole selectively blocks some of the functions within the bacterial cells and the parasites resulting in their death. Metronidazole is usually taken two or three times a day for ten days or longer. Metronidazole comes as a tablet to take by mouth. When administered systemically via oral tablets, Metronidazole works by inhibiting bacterial DNA synthesis hence preventing the replication of bacteria. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection.

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